Category: 2023-2024

This review in ChemBioChem examines the interactions between synthetic cells, tissues, and living counterparts, aiming for full integration. It discusses advancements in synthetic/living cells interactions, prototissue engineering, and stimuli-driven tissue engineering, paving the way for future studies in tissue engineering, synthetic biology, and regenerative medicine. The work was funded by the European Union and Fondazione Istituto di Ricerca Pediatrica Città della Speranza.

This mini-review, published in ChemSystemsChem, introduces the concept of higher-order behavior in materials chemistry, discussing the development of such behaviors in bio-inspired systems like polymer networks, microbots, protocells, and prototissues. It emphasizes the ability to chemically program these materials and their potential applications in various fields, from tissue engineering to regenerative medicine. The work was funded by the European Union (ERC StG, PROTOMAT, 101039578; Marie Curie Postdoctoral Fellowship, PROTO-BACT, 101107715).